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2014 Nobel Prize Laureates: All publications

All publications by Dr. John O'Keefe

Ainsworth A, Gaffan GD, O'Keefe J, Sampson R. A technique for recording units in the medulla of the awake. freely moving rat. J Physiol 1969;202(2).

Ainsworth A, O'Keefe J. A lightweight microdrive for the simultaneous recording of several units in the awake. freely moving rat. J Physiol 1977;269(1).

Barnes CA, McNaughton BL, O'Keefe J. Loss of place specificity in hippocampal complex spike cells of senescent rat. Neurobiol Aging 4(2); 1983.

Barry C, Bush D, O'Keefe J, Burgess N. Models of grid cells and theta oscillations. Nature 488(7409), E1-E2.

Barry C, Lever C, Hayman R, et al. The boundary vector cell model of place cell firing and spatial memory. Reviews in the Neurosciences 17(1-2); 2006.

Basbaum AI, Marley NJ, O'Keefe J, Clanton CH. Reversal of morphine and stimulus-produced analgesia by subtotal spinal cord lesions. Pain 3(1); 1977.

Black AH, Nadel L, O'Keefe J. Hippocampal function in avoidance learning and punishment. Psychol Bull 84(6); 1977.

Burgess N, Barry C, O'Keefe J. An oscillatory interference model of grid cell firing. 2007;17(9):801-812.

Burgess N, Becker S, King J, O'Keefe J. Memory for events and their spatial context: models and experiments. Philosophical Transactions of the Royal Society B: Biological Sciences 356(1413); 2001.

Burgess N, Cacucci F, Lever C, O'Keefe J. Characterizing multiple independent behavioral correlates of cell firing in freely moving animals. Hippocampus 15(2); 2005.

Burgess N, Donnett J, Jeffery K, O'Keefe J. Robotic and neuronal simulation of the hippocampus and navigation. In: N J, K OK, J, editors. Burgess; 1998.

Burgess N, Donnett J, Jeffery K, O'Keefe J. Robotic and neuronal simulation of the hippocampus and rat navigation. Philosophical Transactions of the Royal Society B: Biological Sciences 352(1360); 1997.

Burgess N, Donnett J, O'Keefe J. The representation of space and the hippocampus in rats, robots and humans. Zeitschrift f�r Naturforschung C 53(7-8); 1998.

Burgess N, Donnett J, O'Keefe J. Using a mobile robot to test a model of the rat hippocampus. Connection Science 10(3-4); 1998.

Burgess N, Jackson A, Hartley T, O'Keefe J. Predictions derived from modelling the hippocampal role in navigation. Biol Cybern 2000;83(3):301-312.

Burgess N, Jeffery K, O'Keefe J. Integrating hippocampal and parietal functions: a spatial point of view. In: N J, K OK, J, editors. Burgess; 1998.

Burgess N, Jeffery K, O'Keefe J. The Hippocampal and Parietal Foundations of Spatial Cognition. Oxford, UK Oxford University Press; 1998.

Burgess N, Jeffery KJ, O'Keefe J. What are the parietal and hippocampal contributions to spatial cognition? Discussion - Introduction. Philosophical Transactions of the Royal Society B: Biological Sciences 352(1360); 1997.

Burgess N, Maguire E, O'Keefe J. The human hippocampus and spatial and episodic memory. Neuron 2002;35(4):625-641.

Burgess N, Maguire EA, Spiers HJ, O'Keefe J. A temporoparietal and prefrontal network for retrieving the spatial context of lifelike events. Neuroimage 2001;14(2):439-453.

Burgess N, O’Keefe J, Recce M. Toward a Mechanism for Navigation by the Rat Hippocampus. In: Computation in Neurons and Neural Systems. Boston: Boston : Kluwer Academic Publishers; 1994.  p. 257-262.  (591.188 C738 E)

Burgess N, O'Keefe J. Cognitive graphs, resistive grids, and the hippocampal representation of space. J. Gen. Physiol. 1996;107(6):659-662.

Burgess N, O’Keefe J. Models of place and grid cell firing and theta rhythmicity. Current opinion in neurobiology 2011;21(5):734-744.

Burgess N, O'Keefe J. Neural representations in human spatial memory. Trends Cogn. Sci. (Regul. Ed.) 2003;7(12):517-519.

Burgess N, O'Keefe J. Neuronal computations underlying the firing of place cells and their role in navigation. Hippocampus 1996;6(6):749-762.

Burgess N, O'Keefe J. The theta rhythm. Hippocampus 2005;15(7):825-826.

Burgess N, Recce M, O'Keefe J. Hippocampus: spatial models. In: The handbook of brain theory and neural networks. Cambridge, Mass.: Cambridge, Mass. : MIT Press; 1995:468-472.  (M 612.82 H23 A)

Burton S, Murphy D, Qureshi U, Sutton P, O'Keefe J. Combined lesions of hippocampus and subiculum do not produce deficits in a nonspatial social olfactory memory task. The Journal of Neuroscience 2000;20(14):5468-5475.

Cacucci F, Lever C, Burgess N, O’Keefe J. Topodirectional cells in the hippocampal formation of the rat. Eur J Neurosci. 2000;12(suppl 11):86.

Cacucci F, Lever C, Wills TJ, Burgess N, O'Keefe J. Theta-modulated place-by-direction cells in the hippocampal formation in the rat. The Journal of Neuroscience 2004;24(38):8265-8277.

Cacucci F, Wills TJ, Lever C, Giese KP, O'Keefe J. Experience-dependent increase in CA1 place cell spatial information, but not spatial reproducibility, is dependent on the autophosphorylation of the α-isoform of the calcium/calmodulin-dependent protein kinase II. The Journal of neuroscience 2007;27(29):7854-7859.

Cacucci F, Yi M, Wills TJ, Chapman P, O'Keefe J. Place cell firing correlates with memory deficits and amyloid plaque burden in Tg2576 Alzheimer mouse model. Proceedings of the National Academy of Sciences 2008;105(22):7863-7868.

Hartley T, Burgess N, Lever C, Cacucci F, O'Keefe J. Modeling place fields in terms of the cortical inputs to the hippocampus. Hippocampus 2000;10(4):369-379.

Huxter J, Burgess N, O'Keefe J. Independent rate and temporal coding in hippocampal pyramidal cells. Nature 2003;425(6960):828-832. doi: 10. 1038/nature02058; 2003.

Jackson A, Hartley T, O'Keefe J, Burgess N. A predictive geometric model of place field shape and location. Society for Neuroscience Abstracts 1999;24.

Jeewajee A, Barry C, O'Keefe J, Burgess N. Grid cells and theta as oscillatory interference: electrophysiological data from freely moving rats. Hippocampus 2008;18(12):1175-1185..

Jeewajee A, Lever C, Burton S, O'Keefe J, Burgess N. Environmental novelty is signaled by reduction of the hippocampal theta frequency. Hippocampus 2008;18(4):340-348.

Jeffery K, Donnett JG, Burgess N, O’Keefe JM. Directional control of hippocampal place fields. Exp Brain Res 1997;117(1):131-142.

Jeffery KJ, O’Keefe JM. Learned interaction of visual and idiothetic cues in the control of place field orientation. Exp Brain Res 1999;127(2):151-161.

Jeffery KJ, Donnett JG, Burgess N, O'Keefe J. Poster: Orientation of hippocampal place fields in a symmetrical environment. 14th Annual Meeting of the Brain Research Association; 1997.

Jeffery KJ, Donnett JG, O'Keefe J. Medial septal control of theta-correlated unit firing in the entorhinal cortex of awake rats. Neuroreport 1995;6(16):2166-2170.

Jeffery K, O'Keefe J. Worm holes and avian space-time. Nature 1998;395(6699):215-216.

King C, Recce M, O’Keefe J. The rhythmicity of cells of the medial septum/diagonal band of Broca in the awake freely moving rat: relationships with behaviour and hippocampal theta. European Journal of Neuroscience 1998;10(2):464-477.

King JA, Burgess N, Hartley T, Vargha-Khadem F, O'Keefe J. Allocentric but not egocentric spatial memory is impaired by bilateral damage to the human hippocampus. Society for Neuroscience Abstracts 2001;27.

King JA, Burgess N, Hartley T, Vargha‐Khadem F, O'Keefe J. Human hippocampus and viewpoint dependence in spatial memory. Hippocampus 2002;12(6):811-820.

Krupic J, Bauza M, Burton S, Lever C, O'Keefe J. How environment geometry affects grid cell symmetry and what we can learn from it. Philosophical Transactions of the Royal Society B: Biological Sciences 2014;369(1635):20130188.

Krupic J, Burgess N, O'Keefe J. Neural representations of location composed of spatially periodic bands. Science 2012;337(6096):853-857.

Lever C, Burgess N, Cacucci F, Hartley T, O'Keefe J. What can the hippocampal representation of environmental geometry tell us about Hebbian learning? Biological cybernetics 2002;87(5-6):356-372.

Lever C, Burton S, Jeewajee A, et al. Environmental Novelty Elicits a Later Theta Phase of Firing in CA1 but Not Subiculum. Hippocampus 2010;20(2):229-234.

Lever C, Burton S, Jeewajee A, O'Keefe J, Burgess N. Boundary Vector Cells in the Subiculum of the Hippocampal Formation. J Neurosci 2009;29(31):9771-9777.

Lever C, Burton S, O'Keefe J. Rearing on hind legs, environmental novelty, and the hippocampal formation. Rev Neurosci 2006;17(1-2):111-134.

Lever C, Burton S, Wills TJ, Burgess N, O'Keefe J. Subicular and dorsal CA1 hippocampal neurons react differently to environmental novelty. Society for Neuroscience. 2005;72.

Lever C, Cacucci F, Burgess N, O'Keefe J. Squaring the circle: place fields do not" remap" between environments which differ only in shape. In: Society for Neuroscience Abstracts; 1999. p. 1380.

Lever C, Cacucci F, Wills T, et al. Spatial coding in the hippocampal formation: input, information type, plasticity and behaviour. In: J K, editor. Jeffery; 2003.

Lever C, Jeewajee A, Burton S, O'Keefe J, Burgess N. Hippocampal theta frequency, novelty, and behavior. Hippocampus 2009;19(4):409-410.

Lever C, Wills T, Cacucci F, Burgess N, O'Keefe J. Long-term plasticity in hippocampal place-cell representation of environmental geometry. Nature 2002;416(6876):90-94.

Maguire E, Burgess N, Donnett J, et al. Knowing where and getting there: A human navigation network. Science (80- ) 1998;280(5365):921-924.

Maguire E, Burgess N, O'Keefe J. Human spatial navigation: cognitive maps, sexual dimorphism, and neural substrates. Curr. Opin. Neurobiol. 1999;9(2):171-177.

Maguire E, Frith C, Burgess N, Donnett J, O'Keefe J. Knowing where things are: Parahippocampal involvement in encoding object locations in virtual large-scale space. Cognitive Neuroscience, Journal of 1998;10(1):61-76.

Maguire EA, Burgess N, Donnett JG, Frith CD, O'Keefe JM. Differential involvement of right hippocampus, left hippocampus and inferior parietal cortex in human spatial navigation. In: Society for Neuroscience Abstracts; 1997. p. 2107-2107.

Martin PD, O'Keefe J. Place field dynamics and directionality in a spatial memory task. Brain Res. 1998;783(2):249-261.

McNaughton BL, Barnes CA, O'Keefe J. The contributions of position, direction, and velocity to single unit activity in the hippocampus of freely-moving rats. Exp Brain Res 1983;52(1):41-49.

McNaughton BL, O'Keefe J, Barnes CA. The stereotrode: a new technique for simultaneous isolation of several single units in the central nervous system from multiple unit records. J Neurosci Methods 1983;8(4):391-397.

Morris RG, Garrud P, Rawlins JN, O'Keefe J. Place navigation impaired in rats with hippocampal lesions. Nature 1982;297(5868):681-683.

Nadel L, O'Keefe J, Black A. Slam on the brakes: a critique of Altman, Brunner, and Bayer's response-inhibition model of hippocampal function. Behav Biol 1975;14(2):151-162.

O'Keefe J, Black AH. Single unit and lesion experiments on the sensory inputs to the hippocampal cognitive map. Functions of the septo-hippocampal system 1978(58):179.

O'Keefe J, Bouma H. Complex sensory properties of certain amygadala units in the freely moving cat. Exp Neurol. 1969;23(3):384-398.

O'Keefe J, Burgess N, Donnett J, Jeffery K, Maguire E. Place cells, navigational accuracy, and the human hippocampus. Philosophical Transactions of the Royal Society B: Biological Sciences 1998;353(1373):1333-1340.

O'Keefe J, Burgess N. Dual phase and rate coding in hippocampal place cells: Theoretical significance and relationship to entorhinal grid cells. Hippocampus 2005;15(7):853-866.

O'Keefe J, Burgess N. Geometric determinants of hippocampal place fields. 1995.

O'Keefe J, Burgess N. Geometric determinants of the place fields of hippocampal neurons. Nature 1996;381(6581):425-428.

O'Keefe J, Burgess N. Spatial and temporal determinants of the hippocampal place cell activity. In: T, editor. Ono; 1996. p. 358-373.

O'Keefe J, Burgess N. Theta activity, virtual navigation and the human hippocampus. Trends in Cognitive Sciences 1999;3(11):403-406.

O'Keefe J, Conway DH. Hippocampal place units in the freely moving rat: why they fire where they fire. Exp Brain Res 1978;31(4):573-590.

O'Keefe J, Dostrovsky J. The hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving rat. Brain Res 1971;34(1):171-175.

O'Keefe J, Gaffan D. Response properties of units in the dorsal column nuclei of the freely moving rat: changes as a function of behaviour. Brain Res 1971;31(2):374--375.

O'Keefe J, Nadel L, Keightley S, Kill D. Fornix lesions selectively abolish place learning in the rat. Exp Neurol 1975;48(1):152-166.

O'Keefe J, Nadel L, Willner J. Tuning out irrelevancy? Comments on Solomon's temporal mapping view of the hippocampus. Psychol Bull 1979;86(6):1280-1289.

O'Keefe J, Recce ML. Phase relationship between hippocampal place units and the EEG theta rhythm. Hippocampus. 1993;3(3):317-330..

O'Keefe J, Speakman A. Single unit activity in the rat hippocampus during a spatial memory task. Exp Brain Res 1987;68(1);1-27.

O'Keefe J. A computational theory of the hippocampal cognitive map. Prog Brain Res 1990;83:301-312. (M 612.808 P9)

O'Keefe J. A review of the hippocampal place cells. Prog Neurobiol 1979;13(4):419-439.

O'Keefe J. An allocentric spatial model for the hippocampal cognitive map. Hippocampus. 1991;1(3):230-235.

O'Keefe J. Developmental psychology. Cognitive maps in infants? Nature. 1994;370(6484):19-20.

O'Keefe J. Do hippocampal pyramidal cells signal non-spatial as well as spatial information? Hippocampus 1999;9(4):352-364.

O'Keefe J. Hippocampus, theta, and spatial memory. Curr Opin Neurobiol 1993;3(6):917-924.

O'Keefe J. Hippocampus. In: Encyclopedia of Cognitive Science; 2003. vol 2 p. 336-347. (R 153.03 E5)

O'Keefe J. Place cells. In: Encyclopaedia of Cognitive Science; 2003. vol 3 p. 688-697. (R 153.03 E5)

O'Keefe J. Place units in the hippocampus of the freely moving rat. Exp Neurol 1976;51(1):78-109.

O'Keefe J. Two spatial systems in the rat brain–implications for the neural basis of learning and memory. Prog Brain Res 1983;58:453-464. (MX 612.808 P9)

O'Keefe J. Vector grammar, places, and the functional role of the spatial prepositions in English. In: Van der Zee, E and Slack, J, (eds.) Axes and Vectors in Language and Space. Oxford University Press; 2001. p. 69-85.

O'Keefe JM. Cartography of the mind. MRC News 1997(77):32-34.

Speakman A, O'Keefe J. Hippocampal Complex Spike Cells do not Change Their Place Fields if the Goal is Moved Within a Cue Controlled Environment. Eur J Neurosci. 1990;2(6):544-555.

Spiers H, Burgess N, Hartley T, Vargha-Khadem F, O'Keefe J. Bilateral hippocampal pathology impairs topographical and episodic memory but not visual pattern matching. Hippocampus. 2001;11(6):715-725

Spiers HJ, Burgess N, Maguire EA, et al. Effect of unilateral temporal lobectomy on topographical and episodic memory in a large-scale virtual reality town. European Journal of Neuroscience 12 2000;79. (MS 612.805 E89 J8 N4)

Spiers HJ, Burgess N, Maguire EA, et al. Unilateral temporal lobectomy patients show lateralized topographical and episodic memory deficits in a virtual town. Brain. 2001;124(Pt 12):2476-2489.

Wells CE, Amos DP, Jeewajee A, et al. Novelty and anxiolytic drugs dissociate two components of hippocampal theta in behaving rats. J Neurosci. 2013;33(20):8650-8667.

Wills TJ, Cacucci F, Burgess N, O'Keefe J. Development of the Hippocampal Cognitive Map in Preweanling Rats. Science. 2010;328(5985):1573-1576.

Wills TJ, Cacucci F, Lever C, Burgess N, O'Keefe J. Abrupt shift in hippocampal place cell representation from square-like to circle-like in a morph box. Society for Neuroscience 2005;330.

Wills TJ, Lever C, Cacucci F, Burgess N, O'Keefe J. Attractor dynamics in the hippocampal representation of the local environment. Science. 2005;308(5723):873-876.