2013 Nobel Prize Laureates: Most cited articles

The synaptic vesicle cycle - a cascade of protein-protein interactions

Nature, 375, 6533, Jun 22 1995, Pages 645-653

Sudhof, T. C.

Times Cited: 1627

The synaptic vesicle cycle

Annual Review of Neuroscience, 27, 2004, Pages 509-547

Sudhof, T. C.

Times Cited: 1080

Membrane fusion

Cell, 112, 4, Feb 21 2003, Pages 519-533

Jahn, R., Lang, T., & Sudhof, T. C.

Times Cited: 827

Membrane fusion and exocytosis

Annual Review of Biochemistry, 68, 1999, Pages 863-911

Jahn, R., & Sudhof, T. C.

Times Cited: 823

A transcriptively active complex of app with fe65 and histone acetyltransferase tip60

Science, 293, 5527, Jul 6 2001, Pages 115-120

Cao, X. W., & Sudhof, T. C.

Times Cited: 770

The ldl receptor gene - a mosaic of exons shared with different proteins

Science, 228, 4701, 1985, Pages 815-822

Sudhof, T. C., Goldstein, J. L., Brown, M. S., & Russell, D. W.

Times Cited: 686

Synaptotagmin - a calcium sensor on the synaptic vesicle surface

Science, 256, 5059, May 15 1992, Pages 1021-1025

Brose, N., Petrenko, A. G., Sudhof, T. C., & Jahn, R.

Times Cited: 628

Direct conversion of fibroblasts to functional neurons by defined factors

Nature, 463, 7284, Feb 25 2010, Pages 1035-U1050

Vierbuchen, T., Ostermeier, A., Pang, Z. P., Kokubu, Y., Sudhof, T. C., & Wernig, M.

Times Cited: 614

Phospholipid binding by a synaptic vesicle protein homologous to the regulatory region of protein kinase-c

Nature, 345, 6272, May 17 1990, Pages 260-263

Perin, M. S., Fried, V. A., Mignery, G. A., Jahn, R., & Sudhof, T. C.

Times Cited: 609

Synaptic vesicle membrane-fusion complex - action of clostridial neurotoxins on assembly

Embo Journal, 13, 21, Nov 1 1994, Pages 5051-5061

Hayashi, T., Mcmahon, H., Yamasaki, S., Binz, T., Hata, Y., Sudhof, T. C., et al.

Times Cited: 559

C-2-domains, structure and function of a universal ca2+-binding domain

Journal of Biological Chemistry, 273, 26, Jun 26 1998, Pages 15879-15882

Rizo, J., & Sudhof, T. C.

Times Cited: 532

Ca2+-dependent and ca2+-independent activities of neural and nonneural synaptotagmins

Nature, 375, 6532, Jun 15 1995, Pages 594-599

Li, C., Ullrich, B., Zhang, J. Z., Anderson, R. G. W., Brose, N., & Sudhof, T. C.

Times Cited: 486

Structure of the first c-2 domain of synaptotagmin .1. A novel ca2+/phospholipid-binding fold

Cell, 80, 6, Mar 24 1995, Pages 929-938

Sutton, R. B., Davletov, B. A., Berghuis, A. M., Sudhof, T. C., & Sprang, S. R.

Times Cited: 485

Membrane fusion: Grappling with snare and sm proteins

Science, 323, 5913, Jan 23 2009, Pages 474-477

Sudhof, T. C., & Rothman, J. E.

Times Cited: 484

Proteins of synaptic vesicles involved in exocytosis and membrane recycling

Neuron, 6, 5, May 1991, Pages 665-677

Sudhof, T. C., & Jahn, R.

Times Cited: 474

Synaptic vesicle fusion complex contains unc-18 homolog bound to syntaxin

Nature, 366, 6453, Nov 25 1993, Pages 347-351

Hata, Y., Slaughter, C. A., & Sudhof, T. C.

Times Cited: 474

Structure and expression of the rat inositol 1,4,5-trisphosphate receptor

Journal of Biological Chemistry, 265, 21, Jul 25 1990, Pages 12679-12685

Mignery, G. A., Newton, C. L., Archer, B. T., & Sudhof, T. C.

Times Cited: 452

Neurexins - synaptic cell-surface proteins related to the alpha-latrotoxin receptor and laminin

Science, 257, 5066, Jul 3 1992, Pages 50-56

Ushkaryov, Y. A., Petrenko, A. G., Geppert, M., & Sudhof, T. C.

Times Cited: 436

Synapsins - mosaics of shared and individual domains in a family of synaptic vesicle phosphoproteins

Science, 245, 4925, Sep 29 1989, Pages 1474-1480

Sudhof, T. C., Czernik, A. J., Kao, H. T., Takei, K., Johnston, P. A., Horiuchi, A., et al.

Times Cited: 407

Rim is a putative rab3 effector in regulating synaptic-vesicle fusion

Nature, 388, 6642, Aug 7 1997, Pages 593-598

Wang, Y., Okamoto, M., Schmitz, F., Hofmann, K., & Sudhof, T. C.

Times Cited: 397

Synaptotagmin-i is a high-affinity receptor for clathrin-ap-2 - implications for membrane recycling

Cell, 78, 5, Sep 9 1994, Pages 751-760

Zhang, J. Z., Davletov, B. A., Sudhof, T. C., & Anderson, R. G. W.

Times Cited: 392

Neuroligins and neurexins link synaptic function to cognitive disease

Nature, 455, 7215, Oct 16 2008, Pages 903-911

Sudhof, T. C.

Times Cited: 386

A conformational switch in syntaxin during exocytosis: Role of munc18

Embo Journal, 18, 16, Aug 16 1999, Pages 4372-4382

Dulubova, I., Sugita, S., Hill, S., Hosaka, M., Fernandez, I., Sudhof, T. C., et al.

Times Cited: 370

Alpha-synuclein cooperates with csp alpha in preventing neurodegeneration

Cell, 123, 3, Nov 4 2005, Pages 383-396

Chandra, S., Gallardo, G., Fernandez-Chacon, R., Schluter, O. M., & Sudhof, T. C.

Times Cited: 370

A single c2 domain from synaptotagmin-i is sufficient for high-affinity ca2+/phospholipid binding

Journal of Biological Chemistry, 268, 35, Dec 15 1993, Pages 26386-26390

Davletov, B. A., & Sudhof, T. C.

Times Cited: 353

Synaptotagmins: C-2-domain proteins that regulate membrane traffic

Neuron, 17, 3, Sep 1996, Pages 379-388

Sudhof, T. C., & Rizo, J.

Times Cited: 348

Mutation in ldl receptor - alu-alu recombination deletes exons encoding transmembrane and cytoplasmic domains

Science, 227, 4683, 1985, Pages 140-146

Lehrman, M. A., Schneider, W. J., Sudhof, T. C., Brown, M. S., Goldstein, J. L., & Russell, D. W.

Times Cited: 345

A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain

Cell, 94, 6, Sep 18 1998, Pages 773-782

Butz, S., Okamoto, M., & Sudhof, T. C.

Times Cited: 341

Structure of a novel insp3 receptor

Embo Journal, 10, 11, Nov 1991, Pages 3199-3206

Sudhof, T. C., Newton, C. L., Archer, B. T., Ushkaryov, Y. A., & Mignery, G. A.

Times Cited: 336

Munc13-1 is essential for fusion competence of glutamatergic synoptic vesicles

Nature, 400, 6743, Jul 29 1999, Pages 457-461

Augustin, I., Rosenmund, C., Sudhof, T. C., & Brose, N.

Times Cited: 324

Neuroligin 1 is a postsynaptic cell-adhesion molecule of excitatory synapses

Proceedings of the National Academy of Sciences of the United States of America, 96, 3, Feb 2 1999, Pages 1100-1105

Song, J. Y., Ichtchenko, K., Sudhof, T. C., & Brose, N.

Times Cited: 324

Cask: A novel dlg/psd95 homolog with an n-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins

Journal of Neuroscience, 16, 8, Apr 15 1996, Pages 2488-2494

Hata, Y., Butz, S., & Sudhof, T. C.

Times Cited: 323

Synaptic vesicles and exocytosis

Annual Review of Neuroscience, 17, 1994, Pages 219-246

Jahn, R., & Sudhof, T. C.

Times Cited: 311

Snares and munc18 in synaptic vesicle fusion

Nature Reviews Neuroscience, 3, 8, Aug 2002, Pages 641-653

Rizo, J., & Sudhof, T. C.

Times Cited: 309

Mevinolin, an inhibitor of cholesterol-synthesis, induces messenger-rna for low-density-lipoprotein receptor in livers of hamsters and rabbits

Proceedings of the National Academy of Sciences of the United States of America, 83, 21, Nov 1986, Pages 8370-8374

Ma, P. T. S., Gil, G., Sudhof, T. C., Bilheimer, D. W., Goldstein, J. L., & Brown, M. S.

Times Cited: 308

Proteolysis of snap-25 by type-e and type-a botulinal neurotoxins

Journal of Biological Chemistry, 269, 3, Jan 21 1994, Pages 1617-1620

Binz, T., Blasi, J., Yamasaki, S., Baumeister, A., Link, E., Sudhof, T. C., et al.

Times Cited: 299

Snare function analyzed in synaptobrevin/vamp knockout mice

Science, 294, 5544, Nov 2 2001, Pages 1117-1122

Schoch, S., Deak, F., Konigstorfer, A., Mozhayeva, M., Sara, Y., Sudhof, T. C., et al.

Times Cited: 292

Acid-dependent ligand dissociation and recycling of ldl receptor mediated by growth-factor homology region

Nature, 326, 6115, Apr 23 1987, Pages 760-765

Davis, C. G., Goldstein, J. L., Sudhof, T. C., Anderson, R. G. W., Russell, D. W., & Brown, M. S.

Times Cited: 286

The small gtp-binding protein rab3a regulates a late step in synaptic vesicle fusion

Nature, 387, 6635, Jun 19 1997, Pages 810-814

Geppert, M., Goda, Y., Stevens, C. F., & Sudhof, T. C.

Times Cited: 286

The ligand-binding site and transduction mechanism in the inositol-1,4,5-triphosphate receptor

Embo Journal, 9, 12, Dec 1990, Pages 3893-3898

Mignery, G. A., & Sudhof, T. C.

Times Cited: 284

A small gtp-binding protein dissociates from synaptic vesicles during exocytosis

Nature, 349, 6304, Jan 3 1991, Pages 79-81

Vonmollard, G. F., Sudhof, T. C., & Jahn, R.

Times Cited: 280

Rab geranylgeranyl transferase - a multisubunit enzyme that prenylates gtp-binding proteins terminating in cys-x-cys or cys-cys

Journal of Biological Chemistry, 267, 20, Jul 15 1992, Pages 14497-14503

Seabra, M. C., Goldstein, J. L., Sudhof, T. C., & Brown, M. S.

Times Cited: 271

Complexins - cytosolic proteins that regulate snap receptor function

Cell, 83, 1, Oct 6 1995, Pages 111-119

Mcmahon, H. T., Missler, M., Li, C., & Sudhof, T. C.

Times Cited: 268

A synaptic vesicle protein with a novel cytoplasmic domain and 4 transmembrane regions

Science, 238, 4830, Nov 20 1987, Pages 1142-1144

Sudhof, T. C., Lottspeich, F., Greengard, P., Mehl, E., & Jahn, R.

Times Cited: 264

Domain-structure of synaptotagmin (p65)

Journal of Biological Chemistry, 266, 1, Jan 5 1991, Pages 623-629

Perin, M. S., Brose, N., Jahn, R., & Sudhof, T. C.

Times Cited: 264

Exo-endocytotic recycling of synaptic vesicles in developing processes of cultured hippocampal-neurons

Journal of Cell Biology, 117, 4, May 1992, Pages 849-861

Matteoli, M., Takei, K., Perin, M. S., Sudhof, T. C., & Decamilli, P.

Times Cited: 260

Synaptotagmins: Why so many?

Journal of Biological Chemistry, 277, 10, Mar 8 2002, Pages 7629-7632

Sudhof, T. C.

Times Cited: 258

Sterol-dependent repression of low-density lipoprotein receptor promoter mediated by 16-base pair sequence adjacent to binding-site for transcription factor sp1

Journal of Biological Chemistry, 263, 7, Mar 5 1988, Pages 3372-3379

Dawson, P. A., Hofmann, S. L., Vanderwesthuyzen, D. R., Sudhof, T. C., Brown, M. S., & Goldstein, J. L.

Times Cited: 252

Colocalization of synaptophysin with transferrin receptors - implications for synaptic vesicle biogenesis

Journal of Cell Biology, 115, 1, Oct 1991, Pages 151-164

Cameron, P. L., Sudhof, T. C., Jahn, R., & Decamilli, P.

Times Cited: 250

Bipartite ca2+-binding motif in c-2 domains of synaptotagmin and protein kinase c

Science, 273, 5272, Jul 12 1996, Pages 248-251

Shao, X. G., Davletov, B. A., Sutton, R. B., Sudhof, T. C., & Rizo, J.

Times Cited: 249

Munc13-1 is a presynaptic phorbol ester receptor that enhances neurotransmitter release

Neuron, 21, 1, Jul 1998, Pages 123-136

Betz, A., Ashery, U., Rickmann, M., Augustin, I., Neher, E., Sudhof, T. C., et al.

Times Cited: 249

Mammalian homologs of caenorhabditis-elegans unc-13 gene define novel family of c-2-domain proteins

Journal of Biological Chemistry, 270, 42, Oct 20 1995, Pages 25273-25280

Brose, N., Hofmann, K., Hata, Y., & Sudhof, T. C.

Times Cited: 246

Structures, alternative splicing, and neurexin binding of multiple neuroligins

Journal of Biological Chemistry, 271, 5, Feb 2 1996, Pages 2676-2682

Ichtchenko, K., Nguyen, T., & Sudhof, T. C.

Times Cited: 244

Postsynaptic membrane fusion and long-term potentiation

Science, 279, 5349, Jan 16 1998, Pages 399-403

Lledo, P. M., Zhang, X. Y., Sudhof, T. C., Malenka, R. C., & Nicoll, R. A.

Times Cited: 243

Rab3a is essential for mossy fibre long-term potentiation in the hippocampus

Nature, 388, 6642, Aug 7 1997, Pages 590-593

Castillo, P. E., Janz, R., Sudhof, T. C., Tzounopoulos, T., Malenka, R. C., & Nicoll, R. A.

Times Cited: 242

Ryanodine and inositol trisphosphate receptors coexist in avian cerebellar purkinje neurons

Journal of Cell Biology, 113, 5, Jun 1991, Pages 1145-1157

Walton, P. D., Airey, J. A., Sutko, J. L., Beck, C. F., Mignery, G. A., Sudhof, T. C., et al.

Times Cited: 240

Membrane-fusion machinery - insights from synaptic proteins

Cell, 75, 1, Oct 8 1993, Pages 1-4

Sudhof, T. C., Decamilli, P., Niemann, H., & Jahn, R.

Times Cited: 236

Complexins regulate a late step in ca2+-dependent neurotransmitter release

Cell, 104, 1, Jan 12 2001, Pages 71-81

Reim, K., Mansour, M., Varoqueaux, F., McMahon, H. T., Sudhof, T. C., Brose, N., et al.

Times Cited: 231

Mints, munc18-interacting proteins in synaptic vesicle exocytosis

Journal of Biological Chemistry, 272, 50, Dec 12 1997, Pages 31459-31464

Okamoto, M., & Sudhof, T. C.

Times Cited: 230

Neurexins: Three genes and 1001 products

Trends in Genetics, 14, 1, Jan 1998, Pages 20-26

Missler, M., & Sudhof, T. C.

Times Cited: 228

Association of rab3a with synaptic vesicles at late stages of the secretory pathway

Journal of Cell Biology, 115, 3, Nov 1991, Pages 625-633

Matteoli, M., Takei, K., Cameron, R., Hurlbut, P., Johnston, P. A., Sudhof, T. C., et al.

Times Cited: 224

A stoichiometric complex of neurexins and dystroglycan in brain

Journal of Cell Biology, 154, 2, Jul 23 2001, Pages 435-445

Sugita, S., Saito, F., Tang, J., Satz, J., Campbell, K., & Sudhof, T. C.

Times Cited: 221

Binding of synaptotagmin to the alpha-latrotoxin receptor implicates both in synaptic vesicle exocytosis

Nature, 353, 6339, Sep 5 1991, Pages 65-68

Petrenko, A. G., Perin, M. S., Davletov, B. A., Ushkaryov, Y. A., Geppert, M., & Sudhof, T. C.

Times Cited: 221

Cartography of neurexins - more than 1000 isoforms generated by alternative splicing and expressed in distinct subsets of neurons

Neuron, 14, 3, Mar 1995, Pages 497-507

Ullrich, B., Ushkaryov, Y. A., & Sudhof, T. C.

Times Cited: 220

Coexpression in vertebrate tissues and cell-lines of multiple inositol 1,4,5-trisphosphate (insp(3)) receptors with distinct affinities for insp(3)

Journal of Biological Chemistry, 269, 46, Nov 18 1994, Pages 28613-28619

Newton, C. L., Mignery, G. A., & Sudhof, T. C.

Times Cited: 219

42 bp element from ldl receptor gene confers end-product repression by sterols when inserted into viral tk promoter

Cell, 48, 6, Mar 27 1987, Pages 1061-1069

Sudhof, T. C., Russell, D. W., Brown, M. S., & Goldstein, J. L.

Times Cited: 213

A synaptic vesicle membrane-protein is conserved from mammals to drosophila

Neuron, 2, 5, May 1989, Pages 1475-1481

Sudhof, T. C., Baumert, M., Perin, M. S., & Jahn, R.

Times Cited: 211

Rim1 alpha is required for presynaptic long-term potentiation

Nature, 415, 6869, Jan 17 2002, Pages 327-330

Castillo, P. E., Schoch, S., Schmitz, F., Sudhof, T. C., & Malenka, R. C.

Times Cited: 211

A broken alpha-helix in folded alpha-synuclein

Journal of Biological Chemistry, 278, 17, Apr 25 2003, Pages 15313-15318

Chandra, S., Chen, X. C., Rizo, J., Jahn, R., & Sudhof, T. C.

Times Cited: 210

Purification of component-a of rab geranylgeranyl transferase - possible identity with the choroideremia gene-product

Cell, 70, 6, Sep 18 1992, Pages 1049-1057

Seabra, M. C., Brown, M. S., Slaughter, C. A., Sudhof, T. C., & Goldstein, J. L.

Times Cited: 207

A complexin/synaptotagmin 1 switch controls fast synaptic vesicle exocytosis

Cell, 126, 6, Sep 22 2006, Pages 1175-1187

Tang, J., Maximov, A., Shin, O. H., Dai, H., Rizo, J., & Sudhof, T. C.

Times Cited: 204

Ribeye, a component of synaptic ribbons: A protein's journey through evolution provides insight into synaptic ribbon function

Neuron, 28, 3, Dec 2000, Pages 857-872

Schmitz, F., Konigstorfer, A., & Sudhof, T. C.

Times Cited: 203

Synaptotagmin-ii - a novel differentially distributed form of synaptotagmin

Journal of Biological Chemistry, 266, 21, Jul 25 1991, Pages 13548-13552

Geppert, M., Archer, B. T., & Sudhof, T. C.

Times Cited: 203

Alpha-synuclein promotes snare-complex assembly in vivo and in vitro

Science, 329, 5999, Sep 24 2010, Pages 1663-1667

Burre, J., Sharma, M., Tsetsenis, T., Buchman, V., Etherton, M. R., & Sudhof, T. C.

Times Cited: 200

Three-dimensional structure of an evolutionarily conserved n-terminal domain of syntaxin 1a

Cell, 94, 6, Sep 18 1998, Pages 841-849

Fernandez, I., Ubach, J., Dulubova, I., Zhang, X. Y., Sudhof, T. C., & Rizo, J.

Times Cited: 196

A splice code for trans-synaptic cell adhesion mediated by binding of neuroligin 1 to alpha- and beta-neurexins

Neuron, 48, 2, Oct 20 2005, Pages 229-236

Boucard, A. A., Chubykin, A. A., Comoletti, D., Taylor, P., & Sudhof, T. C.

Times Cited: 195

Association of neuronal calcium channels with modular adaptor proteins

Journal of Biological Chemistry, 274, 35, Aug 27 1999, Pages 24453-24456

Maximov, A., Sudhof, T. C., & Bezprozvanny, I.

Times Cited: 192

Rab3 and synaptotagmin: The yin and yang of synaptic membrane fusion

Annual Review of Neuroscience, 21, 1998, Pages 75-95

Geppert, M., & Sudhof, T. C.

Times Cited: 192

Three-dimensional structure of the complexin/snare complex

Neuron, 33, 3, Jan 31 2002, Pages 397-409

Chen, X. C., Tomchick, D. R., Kovrigin, E., Arac, D., Machius, M., Sudhof, T. C., et al.

Times Cited: 190

Structural and functional conservation of synaptotagmin (p65) in drosophila and humans

Journal of Biological Chemistry, 266, 1, Jan 5 1991, Pages 615-622

Perin, M. S., Johnston, P. A., Ozcelik, T., Jahn, R., Francke, U., & Sudhof, T. C.

Times Cited: 182

The synaptic vesicle cycle revisited

Neuron, 28, 2, Nov 2000, Pages 317-320

Sudhof, T. C.

Times Cited: 182

Dissection of amyloid-beta precursor protein-dependent transcriptional transactivation

Journal of Biological Chemistry, 279, 23, Jun 4 2004, Pages 24601-24611

Cao, X. W., & Sudhof, T. C.

Times Cited: 181

Ca2+ binding to synaptotagmin: How many ca2+ ions bind to the tip of a c-2-domain?

Embo Journal, 17, 14, Jul 15 1998, Pages 3921-3930

Ubach, J., Zhang, X. Y., Shao, X. G., Sudhof, T. C., & Rizo, J.

Times Cited: 177

Isolation of mammalian calelectrins - a new class of ubiquitous ca-2(+)-regulated proteins

Biochemistry, 23, 6, 1984, Pages 1103-1109

Sudhof, T. C., Ebbecke, M., Walker, J. H., Fritsche, U., & Boustead, C.

Times Cited: 177

Rab proteins in regulated exocytosis

Trends in Biochemical Sciences, 19, 4, Apr 1994, Pages 164-168

Vonmollard, G. F., Stahl, B., Li, C., Sudhof, T. C., & Jahn, R.

Times Cited: 167

3 direct repeats and a tata-like sequence are required for regulated expression of the human low-density-lipoprotein receptor gene

Journal of Biological Chemistry, 262, 22, Aug 5 1987, Pages 10773-10779

Sudhof, T. C., Vanderwesthuyzen, D. R., Goldstein, J. L., Brown, M. S., & Russell, D. W.

Times Cited: 164

Gcap39, a calcium ion- and polyphosphoinositide-regulated actin capping protein

Science, 250, 4986, Dec 7 1990, Pages 1413-1415

Yu, F. X., Johnston, P. A., Sudhof, T. C., & Yin, H. L.

Times Cited: 164

The appendage domain of alpha-adaptin is a high-affinity binding-site for dynamin

Journal of Biological Chemistry, 270, 17, Apr 28 1995, Pages 10079-10083

Wang, L. H., Sudhof, T. C., & Anderson, R. G. W.

Times Cited: 164

Synaptotagmin-syntaxin interaction: The c-2 domain as a ca2+-dependent electrostatic switch

Neuron, 18, 1, Jan 1997, Pages 133-142

Shao, X. G., Fernandez, I., Zhang, X. Y., Sudhof, T. C., & Rizo, J.

Times Cited: 161

Ca2+ stores in purkinje neurons - endoplasmic-reticulum subcompartments demonstrated by the heterogeneous distribution of the insp3 receptor, ca2+-atpase, and calsequestrin

Journal of Neuroscience, 12, 2, Feb 1992, Pages 489-505

Takei, K., Stukenbrok, H., Metcalf, A., Mignery, G. A., Sudhof, T. C., Volpe, P., et al.

Times Cited: 160

A phospho-switch controls the dynamic association of synapsins with synaptic vesicles

Neuron, 24, 2, Oct 1999, Pages 377-387

Hosaka, M., Hammer, R. E., & Sudhof, T. C.

Times Cited: 153

Cassette of 8 exons shared by genes for ldl receptor and egf precursor

Science, 228, 4701, 1985, Pages 893-895

Sudhof, T. C., Russell, D. W., Goldstein, J. L., Brown, M. S., Sanchezpescador, R., & Bell, G. I.

Times Cited: 151

Differential expression and regulation of multiple dynamins

Journal of Biological Chemistry, 269, 6, Feb 11 1994, Pages 4547-4554

Sontag, J. M., Fykse, E. M., Ushkaryov, Y., Liu, J. P., Robinson, P. J., & Sudhof, T. C.

Times Cited: 149

Sv2a and sv2b function as redundant ca2+ regulators in neurotransmitter release

Neuron, 24, 4, Dec 1999, Pages 1003-1016

Janz, R., Goda, Y., Geppert, M., Missler, M., & Sudhof, T. C.

Times Cited: 147

Synaptic core complex of synaptobrevin, syntaxin, and snap25 forms high-affinity alpha-snap finding site

Journal of Biological Chemistry, 270, 5, Feb 3 1995, Pages 2213-2217

Mcmahon, H. T., & Sudhof, T. C.

Times Cited: 146

Synaptophysin is targeted to similar microvesicles in cho and pc12-cells

Embo Journal, 8, 10, Oct 1989, Pages 2863-2872

Johnston, P. A., Cameron, P. L., Stukenbrok, H., Jahn, R., Decamilli, P., & Sudhof, T. C.

Times Cited: 146

Transmembrane topography and evolutionary conservation of synaptophysin

Journal of Biological Chemistry, 264, 2, Jan 15 1989, Pages 1268-1273

Johnston, P. A., Jahn, R., & Sudhof, T. C.

Times Cited: 145

A novel ubiquitous form of munc-18 interacts with multiple syntaxins - use of the yeast 2-hybrid system to study interactions between proteins involved in membrane traffic

Journal of Biological Chemistry, 270, 22, Jun 2 1995, Pages 13022-13028

Hata, Y., & Sudhof, T. C.

Times Cited: 142

Solution structures of the ca2+-free and ca2+-bound c(2)a domain of synaptotagmin i: Does ca2+ induce a conformational change?

Biochemistry, 37, 46, Nov 17 1998, Pages 16106-16115

Shao, X. G., Fernandez, I., Sudhof, T. C., & Rizo, J.

Times Cited: 141

Synaptophysin, a major synaptic vesicle protein, is not essential for neurotransmitter release

Proceedings of the National Academy of Sciences of the United States of America, 93, 10, May 14 1996, Pages 4760-4764

McMahon, H. T., Bolshakov, V. Y., Janz, R., Hammer, R. E., Siegelbaum, S. A., & Sudhof, T. C.

Times Cited: 140

Mints as adaptors - direct binding to neurexins and recruitment of munc18

Journal of Biological Chemistry, 275, 51, Dec 22 2000, Pages 39803-39806

Biederer, T., & Sudhof, T. C.

Times Cited: 137

Essential roles in synaptic plasticity for synaptogyrin i and synaptophysin i

Neuron, 24, 3, Nov 1999, Pages 687-700

Janz, R., Sudhof, T. C., Hammer, R. E., Unni, V., Siegelbaum, S. A., & Bolshakov, V. Y.

Times Cited: 135

Genetics of synaptic vesicle function: Toward the complete functional anatomy of an organelle

Annual Review of Physiology, 61, 1999, Pages 753-776

Fernandez-Chacon, R., & Sudhof, T. C.

Times Cited: 135

Binding properties of neuroligin 1 and neurexin 1 beta reveal function as heterophilic cell adhesion molecules

Journal of Biological Chemistry, 272, 41, Oct 10 1997, Pages 26032-26039

Nguyen, T., & Sudhof, T. C.

Times Cited: 132

Munc18-1 binds directly to the neuronal snare complex

Proceedings of the National Academy of Sciences of the United States of America, 104, 8, Feb 20 2007, Pages 2697-2702

Dulubova, I., Khvotchev, M., Liu, S. Q., Huryeva, I., Sudhof, T. C., & Rizo, J.

Times Cited: 132

A dual-ca2+-sensor model for neurotransmitter release in a central synapse

Nature, 450, 7170, Nov 29 2007, Pages 676-U674

Sun, J., Pang, Z. P., Qin, D., Fahim, A. T., Adachi, R., & Sudhof, T. C.

Times Cited: 129

Distinct ca2+-dependent properties of the first and second c-2-domains of synaptotagmin i

Journal of Biological Chemistry, 271, 3, Jan 19 1996, Pages 1262-1265

Sugita, S., Hata, Y., & Sudhof, T. C.

Times Cited: 129

Rab3c is a synaptic vesicle protein that dissociates from synaptic vesicles after stimulation of exocytosis

Journal of Biological Chemistry, 269, 15, Apr 15 1994, Pages 10971-10974

Vonmollard, G. F., Stahl, B., Khokhlatchev, A., Sudhof, T. C., & Jahn, R.

Times Cited: 129

Structures and chromosomal localizations of 2 human genes encoding synaptobrevin-1 and synaptobrevin-2

Journal of Biological Chemistry, 265, 28, Oct 5 1990, Pages 17267-17273

Archer, B. T., Ozcelik, T., Jahn, R., Francke, U., & Sudhof, T. C.

Times Cited: 129

Synaptotagmins form a hierarchy of exocytotic ca2+ sensors with distinct ca2+ affinities

Embo Journal, 21, 3, Feb 1 2002, Pages 270-280

Sugita, S., Shin, O. H., Han, W. P., Lao, Y., & Sudhof, T. C.

Times Cited: 129

Cleavage of amyloid-beta precursor protein and amyloid-beta precursor-like protein by bace 1

Journal of Biological Chemistry, 279, 11, Mar 12 2004, Pages 10542-10550

Li, Q. M., & Sudhof, T. C.

Times Cited: 128

Phosphorylation of rim1 alpha by pka triggers presynaptic long-term potentiation at cerebellar parallel fiber synapses

Cell, 115, 1, Oct 3 2003, Pages 49-60

Lonart, G., Schoch, S., Kaeser, P. S., Larkin, C. J., Sudhof, T. C., & Linden, D. J.

Times Cited: 128

The rim/nim family of neuronal c-2 domain proteins - interactions with rab3 and a new class of src homology 3 domain proteins

Journal of Biological Chemistry, 275, 26, Jun 30 2000, Pages 20033-20044

Wang, Y., Sugita, S., & Sudhof, T. C.

Times Cited: 127

Human 67-kda calelectrin contains a duplication of 4 repeats found in 35-kda lipocortins

Proceedings of the National Academy of Sciences of the United States of America, 85, 3, Feb 1988, Pages 664-668

Sudhof, T. C., Slaughter, C. A., Leznicki, I., Barjon, P., & Reynolds, G. A.

Times Cited: 126

Annexin-vi is required for budding of clathrin-coated pits

Cell, 70, 2, Jul 24 1992, Pages 283-291

Lin, H. C., Sudhof, T. C., & Anderson, R. G. W.

Times Cited: 123

Structure and evolution of neurexin genes: Insight into the mechanism of alternative splicing

Genomics, 79, 6, Jun 2002, Pages 849-859

Tabuchi, K., & Sudhof, T. C.

Times Cited: 121

Distinct ca2+ and sr2+ binding-properties of synaptotagmins - definition of candidate ca2+ sensors for the fast and slow components of neurotransmitter release

Journal of Biological Chemistry, 270, 42, Oct 20 1995, Pages 24898-24902

Li, C., Davletov, B. A., & Sudhof, T. C.

Times Cited: 119

Doc2 proteins in rat brain: Complementary distribution and proposed function as vesicular adapter proteins in early stages of secretion

Neuron, 18, 3, Mar 1997, Pages 453-461

Verhage, M., deVries, K. J., Roshol, H., Burbach, J. P. H., Gispen, W. H., & Sudhof, T. C.

Times Cited: 119

How tlg2p/syntaxin 16 'snares' vps45

Embo Journal, 21, 14, Jul 15 2002, Pages 3620-3631

Dulubova, I., Yamaguchi, T., Gao, Y., Min, S. W., Huryeva, I., Sudhof, T. C., et al.

Times Cited: 118

A trimeric protein complex functions as a synaptic chaperone machine

Neuron, 31, 6, Sep 27 2001, Pages 987-999

Tobaben, S., Thakur, P., Fernandez-Chacon, R., Sudhof, T. C., Rettig, J., & Stahl, B.

Times Cited: 116

Sly1 binds to golgi and er syntaxins via a conserved n-terminal peptide motif

Developmental Cell, 2, 3, Mar 2002, Pages 295-305

Yamaguchi, T., Dulubova, I., Min, S. W., Chen, X. H., Rizo, J., & Sudhof, T. C.

Times Cited: 116

A complete genetic analysis of neuronal rab3 function

Journal of Neuroscience, 24, 29, Jul 21 2004, Pages 6629-6637

Schluter, O. M., Schmitz, F., Jahn, R., Rosenmund, C., & Sudhof, T. C.

Times Cited: 115

Synaptotagmin - a membrane constituent of neuropeptide-containing large dense-core vesicles

Journal of Neuroscience, 13, 9, Sep 1993, Pages 3895-3903

Walchsolimena, C., Takei, K., Marek, K. L., Midyett, K., Sudhof, T. C., Decamilli, P., et al.

Times Cited: 115

Intracellular calcium dependence of large dense-core vesicle exocytosis in the absence of synaptotagmin i

Proceedings of the National Academy of Sciences of the United States of America, 98, 20, Sep 25 2001, Pages 11680-11685

Voets, T., Moser, T., Lund, P. E., Chow, R. H., Geppert, M., Sudhof, T. C., et al.

Times Cited: 113

Human endomembrane h+ pump strongly resembles the atp-synthetase of archaebacteria

Proceedings of the National Academy of Sciences of the United States of America, 86, 16, Aug 1989, Pages 6067-6071

Sudhof, T. C., Fried, V. A., Stone, D. K., Johnston, P. A., & Xie, X. S.

Times Cited: 112

Rab3 reversibly recruits rabphilin to synaptic vesicles by a mechanism analogous to raf recruitment by ras

Embo Journal, 15, 8, Apr 15 1996, Pages 1799-1809

Stahl, B., Chou, J. H., Li, C., Sudhof, T. C., & Jahn, R.

Times Cited: 111

Selective capability of syncam and neuroligin for functional synapse assembly

Journal of Neuroscience, 25, 1, Jan 5 2005, Pages 260-270

Sara, Y., Biederer, T., Atasoy, D., Chubykin, A., Mozhayeva, M. G., Sudhof, T. C., et al.

Times Cited: 111

A role for camp in long-term depression at hippocampal mossy fiber synapses

Neuron, 21, 4, Oct 1998, Pages 837-845

Tzounopoulos, T., Janz, R., Sudhof, T. C., Nicoll, R. A., & Malenka, R. C.

Times Cited: 110

Cell biology of ca2+-triggered exocytosis

Current Opinion in Cell Biology, 22, 4, Aug 2010, Pages 496-505

Pang, Z. P. P., & Sudhof, T. C.

Times Cited: 110

Mechanism of phospholipid binding by the c(2)a-domain of synaptotagmin i

Biochemistry, 37, 36, Sep 8 1998, Pages 12395-12403

Zhang, X. Y., Rizo, J., & Sudhof, T. C.

Times Cited: 110

Histogenesis and differentiation potential of central neurocytomas (no online full text)

Laboratory Investigation, 64, 4, Apr 1991, Pages 585-591

Vondeimling, A., Kleihues, P., Saremaslani, P., Yasargil, M. G., Spoerri, O., Sudhof, T. C., et al.

Times Cited: 108

1st cysteine-rich repeat in ligand-binding domain of low-density-lipoprotein receptor binds ca-2+ and monoclonal-antibodies, but not lipoproteins

Journal of Biological Chemistry, 262, 36, Dec 25 1987, Pages 17443-17449

Vandriel, I. R., Goldstein, J. L., Sudhof, T. C., & Brown, M. S.

Times Cited: 107

Complexin controls the force transfer from snare complexes to membranes in fusion

Science, 323, 5913, Jan 23 2009, Pages 516-521

Maximov, A., Tang, J., Yang, X. F., Pang, Z. P. P., & Sudhof, T. C.

Times Cited: 107

Mechanism of ca2+ inhibition of inositol 1,4,5-trisphosphate (insp3) binding to the cerebellar insp3 receptor

Journal of Biological Chemistry, 267, 11, Apr 15 1992, Pages 7450-7455

Mignery, G. A., Johnston, P. A., & Sudhof, T. C.

Times Cited: 107

The evolutionary pressure to inactivate - a subclass of synaptotagmins with an amino acid substitution that abolishes ca2+ binding

Journal of Biological Chemistry, 272, 22, May 30 1997, Pages 14314-14319

vonPoser, C., Ichtchenko, K., Shao, X. G., Rizo, J., & Sudhof, T. C.

Times Cited: 107

The making of neurexins

Journal of Neurochemistry, 71, 4, Oct 1998, Pages 1339-1347

Missler, M., Fernandez-Chacon, R., & Sudhof, T. C.

Times Cited: 107

Lrrtm2 functions as a neurexin ligand in promoting excitatory synapse formation

Neuron, 64, 6, Dec 24 2009, Pages 791-798

Ko, J., Fuccillo, M. V., Malenka, R. C., & Sudhof, T. C.

Times Cited: 106

Binding of f-spondin to amyloid-beta precursor protein: A candidate amyloid-beta precursor protein ligand that modulates amyloid-beta precursor protein cleavage

Proceedings of the National Academy of Sciences of the United States of America, 101, 8, Feb 24 2004, Pages 2548-2553

Ho, A., & Sudhof, T. C.

Times Cited: 105

A family of rim-binding proteins regulated by alternative splicing: Implications for the genesis of synaptic active zones

Proceedings of the National Academy of Sciences of the United States of America, 99, 22, Oct 29 2002, Pages 14464-14469

Wang, Y., Liu, X. R., Biederer, T., & Sudhof, T. C.

Times Cited: 104

Inositol 1,4,5-trisphosphate receptor causes formation of er cisternal stacks in transfected fibroblasts and in cerebellar purkinje-cells

Neuron, 12, 2, Feb 1994, Pages 327-342

Takei, K., Mignery, G. A., Mugnaini, E., Sudhof, T. C., & Decamilli, P.

Times Cited: 104

Alpha-latrotoxin and its receptors: Neurexins and cirl/latrophilins

Annual Review of Neuroscience, 24, 2001, Pages 933-962

Sudhof, T. C.

Times Cited: 102

Ehsh1/intersectin, a protein that contains eh and sh3 domains and binds to dynamin and snap-25 - a protein connection between exocytosis and endocytosis?

Journal of Biological Chemistry, 274, 26, Jun 25 1999, Pages 18446-18454

Okamoto, M., Schoch, S., & Sudhof, T. C.

Times Cited: 102

A novel family of phosphatidylinositol 4-kinases conserved from yeast to humans

Journal of Biological Chemistry, 276, 11, Mar 16 2001, Pages 7705-7708

Barylko, B., Gerber, S. H., Binns, D. D., Grichine, N., Khvotchev, M., Sudhof, T. C., et al.

Times Cited: 101

Phosphorylation of dynamin-i and synaptic-vesicle recycling

Trends in Neurosciences, 17, 8, Aug 1994, Pages 348-353

Robinson, P. J., Liu, J. P., Powell, K. A., Fykse, E. M., & Sudhof, T. C.

Times Cited: 101

Autonomous function of synaptotagmin 1 in triggering synchronous release independent of asynchronous release

Neuron, 48, 4, Nov 23 2005, Pages 547-554

Maximov, A., & Sudhof, T. C.

Times Cited: 100

Structure of the 116-kda polypeptide of the clathrin-coated vesicle synaptic vesicle proton pump

Journal of Biological Chemistry, 266, 6, Feb 25 1991, Pages 3877-3881

Perin, M. S., Fried, V. A., Stone, D. K., Xie, X. S., & Sudhof, T. C.

Times Cited: 100