SEATTLE, US: Murine models have been instrumental in studying tooth development; however, significant differences in tooth shape, number of cusps, and the timing and sequence of molar development between mice and humans necessitate a deeper understanding of human tooth development to develop effective treatments for dental disorders. Seeking to advance research in enamel regeneration, a recent study has examined the regulatory mechanisms of ameloblasts and investigated how they develop and function. The insights gained have implications for both understanding conditions that affect the enamel and potentially developing regenerative approaches for dental health. (Research article: Single-cell census of human tooth development enables generation of human enamel)
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[Source: Dental Tribune]
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