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Most cited articles

Mechanism of intracellular protein-transport

Nature, 372, 6501, Nov 3 1994, Pages 55-63

Rothman, J. E.

Times Cited: 1868

A protein assembly-disassembly pathway in-vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion

Cell, 75, 3, Nov 5 1993, Pages 409-418

Sollner, T., Bennett, M. K., Whiteheart, S. W., Scheller, R. H., & Rothman, J. E.

Times Cited: 1299

Visualizing secretion and synaptic transmission with ph-sensitive green fluorescent proteins

Nature, 394, 6689, Jul 9 1998, Pages 192-195

Miesenbock, G., De Angelis, D. A., & Rothman, J. E.

Times Cited: 956

Protein sorting by transport vesicles

Science, 272, 5259, Apr 12 1996, Pages 227-234

Rothman, J. E., & Wieland, F. T.

Times Cited: 911

Molecular dissection of the secretory pathway

Nature, 355, 6359, Jan 30 1992, Pages 409-415

Rothman, J. E., & Orci, L.

Times Cited: 901

Biosynthetic protein-transport and sorting by the endoplasmic-reticulum and golgi

Annual Review of Biochemistry, 56, 1987, Pages 829-852

Pfeffer, S. R., & Rothman, J. E.

Times Cited: 859

Polypeptide-chain binding-proteins - catalysts of protein folding and related processes in cells

Cell, 59, 4, Nov 17 1989, Pages 591-601

Rothman, J. E.

Times Cited: 839

Membrane asymmetry

Science, 195, 4280, 1977, Pages 743-753

Rothman, J. E., & Lenard, J.

Times Cited: 817

Peptide binding and release by proteins implicated as catalysts of protein assembly

Science, 245, 4916, Jul 28 1989, Pages 385-390

Flynn, G. C., Chappell, T. G., & Rothman, J. E.

Times Cited: 652

Peptide-binding specificity of the molecular chaperone bip

Nature, 353, 6346, Oct 24 1991, Pages 726-730

Flynn, G. C., Pohl, J., Flocco, M. T., & Rothman, J. E.

Times Cited: 585

Reconstitution of the transport of protein between successive compartments of the golgi measured by the coupled incorporation of n-acetylglucosamine

Cell, 39, 2, 1984, Pages 405-416

Balch, W. E., Dunphy, W. G., Braell, W. A., & Rothman, J. E.

Times Cited: 544

Inhibition by brefeldin-a of a golgi membrane enzyme that catalyzes exchange of guanine-nucleotide bound to arf

Nature, 360, 6402, Nov 26 1992, Pages 352-354

Helms, J. B., & Rothman, J. E.

Times Cited: 517

Uncoating atpase is a member of the 70 kilodalton family of stress proteins

Cell, 45, 1, Apr 11 1986, Pages 3-13

Chappell, T. G., Welch, W. J., Schlossman, D. M., Palter, K. B., Schlesinger, M. J., & Rothman, J. E.

Times Cited: 510

Membrane fusion: Grappling with snare and sm proteins

Science, 323, 5913, Jan 23 2009, Pages 474-477

Sudhof, T. C., & Rothman, J. E.

Times Cited: 484

Implications of the snare hypothesis for intracellular membrane topology and dynamics

Current Biology, 4, 3, Mar 1 1994, Pages 220-233

Rothman, J. E., & Warren, G.

Times Cited: 479

Synchronized transmembrane insertion and glycosylation of a nascent membrane-protein

Nature, 269, 5631, 1977, Pages 775-780

Rothman, J. E., & Lodish, H. F.

Times Cited: 476

Adp-ribosylation factor is a subunit of the coat of golgi-derived cop-coated vesicles - a novel role for a gtp-binding protein

Cell, 67, 2, Oct 18 1991, Pages 239-253

Serafini, T., Orci, L., Amherdt, M., Brunner, M., Kahn, R. A., & Rothman, J. E.

Times Cited: 467

Purification of an n-ethylmaleimide-sensitive protein catalyzing vesicular transport

Proceedings of the National Academy of Sciences of the United States of America, 85, 21, Nov 1988, Pages 7852-7856

Block, M. R., Glick, B. S., Wilcox, C. A., Wieland, F. T., & Rothman, J. E.

Times Cited: 417

The rate of bulk flow from the endoplasmic-reticulum to the cell-surface

Cell, 50, 2, Jul 17 1987, Pages 289-300

Wieland, F. T., Gleason, M. L., Serafini, T. A., & Rothman, J. E.

Times Cited: 415

Coatomer - a cytosolic protein complex containing subunits of non-clathrin-coated golgi transport vesicles

Nature, 349, 6306, Jan 17 1991, Pages 248-251

Waters, M. G., Serafini, T., & Rothman, J. E.

Times Cited: 387

The golgi-apparatus - 2 organelles in tandem

Science, 213, 4513, 1981, Pages 1212-1219

Rothman, J. E.

Times Cited: 387

Compartmental organization of the golgi stack

Cell, 42, 1, 1985, Pages 13-21

Dunphy, W. G., & Rothman, J. E.

Times Cited: 384

Snaps, a family of nsf attachment proteins involved in intracellular membrane-fusion in animals and yeast

Cell, 61, 4, May 18 1990, Pages 709-721

Clary, D. O., Griff, I. C., & Rothman, J. E.

Times Cited: 384

A new type of coated vesicular carrier that appears not to contain clathrin - its possible role in protein-transport within the golgi stack

Cell, 46, 2, Jul 18 1986, Pages 171-184

Orci, L., Glick, B. S., & Rothman, J. E.

Times Cited: 371

Membrane assembly invitro - synthesis, glycosylation, and asymmetric insertion of a transmembrane protein

Proceedings of the National Academy of Sciences of the United States of America, 74, 8, 1977, Pages 3278-3282

Katz, F. N., Rothman, J. E., Lingappa, V. R., Blobel, G., & Lodish, H. F.

Times Cited: 365

An enzyme that removes clathrin coats - purification of an uncoating atpase

Journal of Cell Biology, 99, 2, 1984, Pages 723-733

Schlossman, D. M., Schmid, S. L., Braell, W. A., & Rothman, J. E.

Times Cited: 339

Purification of a novel class of coated vesicles mediating biosynthetic protein-transport through the golgi stack

Cell, 58, 2, Jul 28 1989, Pages 329-336

Malhotra, V., Serafini, T., Orci, L., Shepherd, J. C., & Rothman, J. E.

Times Cited: 332

The binding of ap-1 clathrin adapter particles to golgi membranes requires adp-ribosylation factor, a small gtp-binding protein

Cell, 73, 5, Jun 4 1993, Pages 999-1005

Stamnes, M. A., & Rothman, J. E.

Times Cited: 328

N-ethylmaleimide-sensitive fusion protein - a trimeric atpase whose hydrolysis of atp is required for membrane-fusion

Journal of Cell Biology, 126, 4, Aug 1994, Pages 945-954

Whiteheart, S. W., Rossnagel, K., Buhrow, S. A., Brunner, M., Jaenicke, R., & Rothman, J. E.

Times Cited: 309

Role of an n-ethylmaleimide-sensitive transport component in promoting fusion of transport vesicles with cisternae of the golgi stack

Cell, 54, 2, Jul 15 1988, Pages 221-227

Malhotra, V., Orci, L., Glick, B. S., Block, M. R., & Rothman, J. E.

Times Cited: 290

Receptor-mediated uptake of antigen/heat shock protein complexes results in major histocompatibility complex class i antigen presentation via two distinct processing pathways

Journal of Experimental Medicine, 191, 11, Jun 5 2000, Pages 1957-1964

Castellino, F., Boucher, P. E., Eichelberg, K., Mayhew, M., Rothman, J. E., Houghton, A. N., et al.

Times Cited: 289

Binding of coatomer to golgi membranes requires adp-ribosylation factor

Journal of Biological Chemistry, 268, 16, Jun 5 1993, Pages 12083-12089

Palmer, D. J., Helms, J. B., Beckers, C. J. M., Orci, L., & Rothman, J. E.

Times Cited: 274

Attachment of terminal n-acetylglucosamine to asparagine-linked oligosaccharides occurs in central cisternae of the golgi stack

Cell, 40, 2, 1985, Pages 463-472

Dunphy, W. G., Brands, R., & Rothman, J. E.

Times Cited: 258

Bimodal interaction of coatomer with the p24 family of putative cargo receptors

Science, 273, 5280, Sep 6 1996, Pages 1396-1399

Fiedler, K., Veit, M., Stamnes, M. A., & Rothman, J. E.

Times Cited: 252

Characterization of protein-transport between successive compartments of the golgi-apparatus - asymmetric properties of donor and acceptor activities in a cell-free system (No online full text)

Archives of Biochemistry and Biophysics, 240, 1, 1985, Pages 413-425

Balch, W. E., & Rothman, J. E.

Times Cited: 252

The atpase core of a clathrin uncoating protein

Journal of Biological Chemistry, 262, 2, Jan 15 1987, Pages 746-751

Chappell, T. G., Konforti, B. B., Schmid, S. L., & Rothman, J. E.

Times Cited: 249

Vesicular transport between the endoplasmic-reticulum and the golgi stack requires the nem-sensitive fusion protein

Nature, 339, 6223, Jun 1 1989, Pages 397-398

Beckers, C. J. M., Block, M. R., Glick, B. S., Rothman, J. E., & Balch, W. E.

Times Cited: 237

Dissection of a single round of vesicular transport - sequential intermediates for intercisternal movement in the golgi stack

Cell, 56, 3, Feb 10 1989, Pages 357-368

Orci, L., Malhotra, V., Amherdt, M., Serafini, T., & Rothman, J. E.

Times Cited: 236

Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagmin

Proceedings of the National Academy of Sciences of the United States of America, 93, 23, Nov 12 1996, Pages 13327-13332

Schiavo, G., Gu, Q. M., Prestwich, G. D., Sollner, T. H., & Rothman, J. E.

Times Cited: 230

Possible role for fatty acyl-coenzyme-a in intracellular protein-transport

Nature, 326, 6110, Mar 19 1987, Pages 309-312

Glick, B. S., & Rothman, J. E.

Times Cited: 230

Binding of the synaptic vesicle v-snare, synaptotagmin, to the plasma membrane t-snare, snap-25, can explain docked vesicles at neurotoxin-treated synapses

Proceedings of the National Academy of Sciences of the United States of America, 94, 3, Feb 4 1997, Pages 997-1001

Schiavo, G., Stenbeck, G., Rothman, J. E., & Sollner, T. H.

Times Cited: 229

Vesicle fusion following receptor-mediated endocytosis requires a protein active in golgi transport

Nature, 339, 6223, Jun 1 1989, Pages 398-400

Diaz, R., Mayorga, L. S., Weidman, P. J., Rothman, J. E., & Stahl, P. D.

Times Cited: 226

Coated vesicles transport newly synthesized membrane-glycoproteins from endoplasmic-reticulum to plasma-membrane in 2 successive stages

Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences, 77, 2, 1980, Pages 780-784

Rothman, J. E., & Fine, R. E.

Times Cited: 218

A multisubunit particle implicated in membrane-fusion

Journal of Cell Biology, 117, 3, May 1992, Pages 531-538

Wilson, D. W., Whiteheart, S. W., Wiedmann, M., Brunner, M., & Rothman, J. E.

Times Cited: 216

Asymmetric exchange of vesicle phospholipids catalyzed by phosphatidylcholine exchange protein - measurement of inside-outside transitions

Biochemistry, 14, 13, 1975, Pages 2809-2816

Rothman, J. E., & Dawidowicz, E. A.

Times Cited: 209

Planar organization of lecithin-cholesterol bilayers

Journal of Biological Chemistry, 247, 11, 1972, Pages 3694-&

Engelman, D. M., & Rothman, J. E.

Times Cited: 206

Early and late functions associated with the golgi-apparatus reside in distinct compartments

Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences, 78, 12, 1981, Pages 7453-7457

Dunphy, W. G., Fries, E., Urbani, L. J., & Rothman, J. E.

Times Cited: 203

Selective activation of cognate snarepins by sec1/munc18 proteins

Cell, 128, 1, Jan 12 2007, Pages 183-195

Shen, J. S., Tareste, D. C., Paumet, F., Rothman, J. E., & Melia, T. J.

Times Cited: 201

Enzymatic recycling of clathrin from coated vesicles

Cell, 46, 1, Jul 4 1986, Pages 5-9

Rothman, J. E., & Schmid, S. L.

Times Cited: 200

Hydrolysis of bound gtp by arf protein triggers uncoating of golgi-derived cop-coated vesicles

Journal of Cell Biology, 123, 6, Dec 1993, Pages 1365-1371

Tanigawa, G., Orci, L., Amherdt, M., Ravazzola, M., Helms, J. B., & Rothman, J. E.

Times Cited: 189

Rapid and efficient fusion of phospholipid vesicles by the alpha-helical core of a snare complex in the absence of an n-terminal regulatory domain

Proceedings of the National Academy of Sciences of the United States of America, 96, 22, Oct 26 1999, Pages 12565-12570

Parlati, F., Weber, T., McNew, J. A., Westermann, B., Sollner, T. H., & Rothman, J. E.

Times Cited: 183

A novel 115-kd peripheral membrane-protein is required for intercisternal transport in the golgi stack

Journal of Cell Biology, 118, 5, Sep 1992, Pages 1015-1026

Waters, M. G., Clary, D. O., & Rothman, J. E.

Times Cited: 179

Compartmentation of asparagine-linked oligosaccharide processing in the golgi-apparatus

Journal of Cell Biology, 97, 1, 1983, Pages 270-275

Dunphy, W. G., & Rothman, J. E.

Times Cited: 176

The use of phluorins for optical measurements of presynaptic activity

Biophysical Journal, 79, 4, Oct 2000, Pages 2199-2208

Sankaranarayanan, S., De Angelis, D., Rothman, J. E., & Ryan, T. A.

Times Cited: 174

Protein sorting by selective retention in the endoplasmic-reticulum and golgi stack

Cell, 50, 4, Aug 14 1987, Pages 521-522

Rothman, J. E.

Times Cited: 172

Sequential intermediates in the pathway of intercompartmental transport in a cell-free system

Cell, 39, 3, 1984, Pages 525-536

Balch, W. E., Glick, B. S., & Rothman, J. E.

Times Cited: 172

Transport of vesicular stomatitis-virus glycoprotein in a cell-free-extract

Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences, 77, 7, 1980, Pages 3870-3874

Fries, E., & Rothman, J. E.

Times Cited: 172

Coated vesicle assembly in the golgi requires only coatomer and arf proteins from the cytosol

Nature, 364, 6439, Aug 19 1993, Pages 732-734

Orci, L., Palmer, D. J., Amherdt, M., & Rothman, J. E.

Times Cited: 171

Molecular mechanism for interaction of phospholipid with cholesterol

Nature-New Biology, 237, 71, 1972, Pages 42-&

Rothman, J. E., & Engelman, D. M.

Times Cited: 169

Autophagy-mediated clearance of huntingtin aggregates triggered by the insulin-signaling pathway

Journal of Cell Biology, 172, 5, Feb 27 2006, Pages 719-731

Yamamoto, A., Cremona, M. L., & Rothman, J. E.

Times Cited: 160

Multiple palmitoylation of synaptotagmin and the t-snare snap-25

Febs Letters, 385, 1-2, Apr 29 1996, Pages 119-123

Veit, M., Sollner, T. H., & Rothman, J. E.

Times Cited: 157

A clamping mechanism involved in snare-dependent exocytosis

Science, 313, 5787, Aug 4 2006, Pages 676-680

Giraudo, C. G., Eng, W. S., Melia, T. J., & Rothman, J. E.

Times Cited: 156

The debate about transport in the golgi - two sides of the same coin?

Cell, 102, 6, Sep 15 2000, Pages 713-719

Pelham, H. R. B., & Rothman, J. E.

Times Cited: 156

A possible docking and fusion particle for synaptic transmission

Nature, 378, 6558, Dec 14 1995, Pages 733-736

Schiavo, G., Gmachl, M. J. S., Stenbeck, G., Sollner, T. H., & Rothman, J. E.

Times Cited: 155

Domain-structure of an n-ethylmaleimide-sensitive fusion protein involved in vesicular transport

Journal of Biological Chemistry, 268, 4, Feb 5 1993, Pages 2662-2666

Tagaya, M., Wilson, D. W., Brunner, M., Arango, N., & Rothman, J. E.

Times Cited: 155

Topological restriction of snare-dependent membrane fusion

Nature, 407, 6801, Sep 14 2000, Pages 194-198

Parlati, F., McNew, J. A., Fukuda, R., Miller, R., Sollner, T. H., & Rothman, J. E.

Times Cited: 155

Positive cooperativity in the functioning of molecular chaperone groel

Journal of Biological Chemistry, 267, 10, Apr 5 1992, Pages 6796-6800

Bochkareva, E. S., Lissin, N. M., Flynn, G. C., Rothman, J. E., & Girshovich, A. S.

Times Cited: 144

Transport of the membrane glycoprotein of vesicular stomatitis-virus to the cell-surface in 2 stages by clathrin-coated vesicles

Journal of Cell Biology, 86, 1, 1980, Pages 162-171

Rothman, J. E., Bursztynpettegrew, H., & Fine, R. E.

Times Cited: 143

Binding of an n-ethylmaleimide sensitive fusion protein to golgi membranes requires both a soluble protein(s) and an integral membrane-receptor

Journal of Cell Biology, 108, 5, May 1989, Pages 1589-1596

Weidman, P. J., Melancon, P., Block, M. R., & Rothman, J. E.

Times Cited: 142

Movement of proteins through the golgi stack - a molecular dissection of vesicular transport

Faseb Journal, 4, 5, Mar 1990, Pages 1460-1468

Rothman, J. E., & Orci, L.

Times Cited: 140

Intercompartmental transport in the golgi-complex is a dissociative process - facile transfer of membrane-protein between 2 golgi populations

Journal of Cell Biology, 99, 1, 1984, Pages 260-271

Rothman, J. E., Miller, R. L., & Urbani, L. J.

Times Cited: 137

Content mixing and membrane integrity during membrane fusion driven by pairing of isolated v-snares and t-snares

Proceedings of the National Academy of Sciences of the United States of America, 96, 22, Oct 26 1999, Pages 12571-12576

Nickel, W., Weber, T., McNew, J. A., Parlati, F., Sollner, T. H., & Rothman, J. E.

Times Cited: 136

Budding from golgi membranes requires the coatomer complex of non-clathrin coat proteins

Nature, 362, 6421, Apr 15 1993, Pages 648-652

Orci, L., Palmer, D. J., Ravazzola, M., Perrelet, A., Amherdt, M., & Rothman, J. E.

Times Cited: 134

Neurotransmission harnessing fusion machinery at the synapse

Trends in Neurosciences, 17, 8, Aug 1994, Pages 344-348

Sollner, T., & Rothman, J. E.

Times Cited: 132

Rapid transmembrane movement of newly synthesized phospholipids during membrane assembly

Proceedings of the National Academy of Sciences of the United States of America, 74, 5, 1977, Pages 1821-1825

Rothman, J. E., & Kennedy, E. P.

Times Cited: 130

Fusion of cells by flipped snares

Science, 300, 5626, Jun 13 2003, Pages 1745-1749

Hu, C., Ahmed, M., Melia, T. J., Sollner, T. H., Mayer, T., & Rothman, J. E.

Times Cited: 128

The yeast sec17 gene-product is functionally equivalent to mammalian alpha-snap protein

Journal of Biological Chemistry, 267, 17, Jun 15 1992, Pages 12106-12115

Griff, I. C., Schekman, R., Rothman, J. E., & Kaiser, C. A.

Times Cited: 125

Purification of 3 related peripheral membrane-proteins needed for vesicular transport

Journal of Biological Chemistry, 265, 17, Jun 15 1990, Pages 10109-10117

Clary, D. O., & Rothman, J. E.

Times Cited: 124

An unfolding story of protein translocation

Nature, 322, 6076, Jul 17 1986, Pages 209-210

Rothman, J. E., & Kornberg, R. D.

Times Cited: 118

Dissociation of clathrin coats coupled to the hydrolysis of atp - role of an uncoating atpase

Journal of Cell Biology, 99, 2, 1984, Pages 734-741

Braell, W. A., Schlossman, D. M., Schmid, S. L., & Rothman, J. E.

Times Cited: 117

The protein machinery of vesicle budding and fusion

Protein Science, 5, 2, Feb 1996, Pages 185-194

Rothman, J. E.

Times Cited: 116

Transbilayer phospholipid asymmetry and its maintenance in membrane of influenza-virus

Biochemistry, 15, 11, 1976, Pages 2361-2370

Rothman, J. E., Tsai, D. K., Dawidowicz, E. A., & Lenard, J.

Times Cited: 115

Asymmetrical distribution of phospholipids in membrane of bacillus-megaterium (No online full text)

Journal of Molecular Biology, 110, 3, 1977, Pages 603-618

Rothman, J. E., & Kennedy, E. P.

Times Cited: 112

2 distinct populations of arf bound to golgi membranes

Journal of Cell Biology, 121, 4, May 1993, Pages 751-760

Helms, J. B., Palmer, D. J., & Rothman, J. E.

Times Cited: 111

Fatty acylation promotes fusion of transport vesicles with golgi cisternae

Journal of Cell Biology, 110, 4, Apr 1990, Pages 955-961

Pfanner, N., Glick, B. S., Arden, S. R., & Rothman, J. E.

Times Cited: 108

The capacity to retrieve escaped er proteins extends to the trans-most cisterna of the golgi stack

Journal of Cell Biology, 129, 2, Apr 1995, Pages 309-319

Miesenbock, G., & Rothman, J. E.

Times Cited: 102

The length of the flexible snarepin juxtamembrane region is a critical determinant of snare-dependent fusion

Molecular Cell, 4, 3, Sep 1999, Pages 415-421

McNew, J. A., Weber, T., Engelman, D. M., Sollner, T. H., & Rothman, J. E.

Times Cited: 100

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