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Most cited articles

A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides

Nature, 332, 6167, Apr 28 1988, Pages 800-805

Deshaies, R. J., Koch, B. D., Wernerwashburne, M., Craig, E. A., & Schekman, R.

Times Cited: 1224

Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway

Cell, 21, 1, 1980, Pages 205-215

Novick, P., Field, C., & Schekman, R.

Times Cited: 1168

Coat proteins and vesicle budding

Science, 271, 5255, Mar 15 1996, Pages 1526-1533

Schekman, R., & Orci, L.

Times Cited: 727

Order of events in the yeast secretory pathway

Cell, 25, 2, 1981, Pages 461-469

Novick, P., Ferro, S., & Schekman, R.

Times Cited: 614

Distinct sets of sec genes govern transport vesicle formation and fusion early in the secretory pathway

Cell, 61, 4, May 18 1990, Pages 723-733

Kaiser, C. A., & Schekman, R.

Times Cited: 524

Early stages in the yeast secretory pathway are required for transport of carboxypeptidase-y to the vacuole

Cell, 30, 2, 1982, Pages 439-448

Stevens, T., Esmon, B., & Schekman, R.

Times Cited: 488

Vesicle-mediated protein sorting

Annual Review of Biochemistry, 61, 1992, Pages 471-516

Pryer, N. K., Wuestehube, L. J., & Schekman, R.

Times Cited: 421

Bi-directional protein transport between the er and golgi

Annual Review of Cell and Developmental Biology, 20, 2004, Pages 87-123

Lee, M. C. S., Miller, E. A., Goldberg, J., Orci, L., & Schekman, R.

Times Cited: 415

Copii-coated vesicle formation reconstituted with purified coat proteins and chemically defined liposomes

Cell, 93, 2, Apr 17 1998, Pages 263-275

Matsuoka, K., Orci, L., Amherdt, M., Bednarek, S. Y., Hamamoto, S., Schekman, R., et al.

Times Cited: 367

Glycosylation and processing of prepro-alpha-factor through the yeast secretory pathway

Cell, 36, 2, 1984, Pages 309-318

Julius, D., Schekman, R., & Thorner, J.

Times Cited: 351

Rna synthesis initiates in-vitro conversion of m13 DNA to its replicative form

Proceedings of the National Academy of Sciences of the United States of America, 69, 4, 1972, Pages 965-&

Wickner, W., Schekman, R., Brutlag, D., & Kornberg, A.

Times Cited: 341

Secretion and cell-surface growth are blocked in a temperature-sensitive mutant of saccharomyces-cerevisiae

Proceedings of the National Academy of Sciences of the United States of America, 76, 4, 1979, Pages 1858-1862

Novick, P., & Schekman, R.

Times Cited: 341

Sec61p and bip directly facilitate polypeptide translocation into the er

Cell, 69, 2, Apr 17 1992, Pages 353-365

Sanders, S. L., Whitfield, K. M., Vogel, J. P., Rose, M. D., & Schekman, R. W.

Times Cited: 313

Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation

Embo Journal, 16, 15, Aug 1 1997, Pages 4540-4548

Pilon, M., Schekman, R., & Romisch, K.

Times Cited: 293

Possible role for rna polymerase in initiation of m13 DNA synthesis

Proceedings of the National Academy of Sciences of the United States of America, 68, 11, 1971, Pages 2826-&

Brutlag, D., Schekman, R., & Kornberg, A.

Times Cited: 292

A yeast mutant defective at an early stage in import of secretory protein precursors into the endoplasmic-reticulum

Journal of Cell Biology, 105, 2, Aug 1987, Pages 633-645

Deshaies, R. J., & Schekman, R.

Times Cited: 288

Membrane-fusion and the cell-cycle - cdc48p participates in the fusion of er membranes

Cell, 82, 6, Sep 22 1995, Pages 885-893

Latterich, M., Frohlich, K. U., & Schekman, R.

Times Cited: 275

Sec12 encodes a guanine-nucleotide-exchange factor essential for transport vesicle budding from the er

Nature, 365, 6444, Sep 23 1993, Pages 347-349

Barlowe, C., & Schekman, R.

Times Cited: 275

Reconstitution of sec gene product-dependent intercompartmental protein-transport

Cell, 54, 3, Jul 29 1988, Pages 335-344

Baker, D., Hicke, L., Rexach, M., Schleyer, M., & Schekman, R.

Times Cited: 269

Protein translocation mutants defective in the insertion of integral membrane-proteins into the endoplasmic-reticulum

Molecular Biology of the Cell, 3, 2, Feb 1992, Pages 129-142

Stirling, C. J., Rothblatt, J., Hosobuchi, M., Deshaies, R., & Schekman, R.

Times Cited: 260

Distinct biochemical requirements for the budding, targeting, and fusion of er-derived transport vesicles

Journal of Cell Biology, 114, 2, Jul 1991, Pages 219-229

Rexach, M. F., & Schekman, R. W.

Times Cited: 259

Compartmentalized assembly of oligosaccharides on exported glycoproteins in yeast

Cell, 25, 2, 1981, Pages 451-460

Esmon, B., Novick, P., & Schekman, R.

Times Cited: 258

Copii-cargo interactions direct protein sorting into er-derived transport vesicles

Nature, 391, 6663, Jan 8 1998, Pages 187-190

Kuehn, M. J., Herrmann, J. M., & Schekman, R.

Times Cited: 257

Multiple genes are required for proper insertion of secretory proteins into the endoplasmic-reticulum in yeast

Journal of Cell Biology, 109, 6, Dec 1989, Pages 2641-2652

Rothblatt, J. A., Deshaies, R. J., Sanders, S. L., Daum, G., & Schekman, R.

Times Cited: 248

Assembly of yeast sec proteins involved in translocation into the endoplasmic-reticulum into a membrane-bound multisubunit complex

Nature, 349, 6312, Feb 28 1991, Pages 806-808

Deshaies, R. J., Sanders, S. L., Feldheim, D. A., & Schekman, R.

Times Cited: 222

Requirement for a gtpase-activating protein in vesicle budding from the endoplasmic-reticulum

Science, 259, 5100, Mar 5 1993, Pages 1466-1468

Yoshihisa, T., Barlowe, C., & Schekman, R.

Times Cited: 222

Copi- and copii-coated vesicles bud directly from the endoplasmic reticulum in yeast

Cell, 83, 7, Dec 29 1995, Pages 1183-1196

Bednarek, S. Y., Ravazzola, M., Hosobuchi, M., Amherdt, M., Perrelet, A., Schekman, R., et al.

Times Cited: 217

Sar1p n-terminal helix initiates membrane curvature and completes the fission of a copii vesicle

Cell, 122, 4, Aug 26 2005, Pages 605-617

Lee, M. C. S., Orci, L., Hamamoto, S., Futai, E., Ravazzola, M., & Schekman, R.

Times Cited: 216

A sec63p-bip complex from yeast is required for protein translocation in a reconstituted proteoliposome

Journal of Cell Biology, 123, 6, Dec 1993, Pages 1355-1363

Brodsky, J. L., & Schekman, R.

Times Cited: 213

Functional compartments of the yeast golgi-apparatus are defined by the sec7 mutation

Embo Journal, 8, 9, Sep 1989, Pages 2695-2702

Franzusoff, A., & Schekman, R.

Times Cited: 212

Initiation of DNA-synthesis .3. Synthesis of phix174 replicative form requires rna synthesis resistant to rifampicin

Proceedings of the National Academy of Sciences of the United States of America, 69, 9, 1972, Pages 2691-&

Schekman, R., Wickner, W., Westerga.O, Kornberg, A., Brutlag, D., Bertsch, L. L., et al.

Times Cited: 212

Lyticase - endoglucanase and protease activities that act together in yeast-cell lysis

Journal of Bacteriology, 142, 2, 1980, Pages 414-423

Scott, J. H., & Schekman, R.

Times Cited: 212

A membrane glycoprotein, sec12p, required for protein-transport from the endoplasmic-reticulum to the golgi-apparatus in yeast

Journal of Cell Biology, 107, 3, Sep 1988, Pages 851-863

Nakano, A., Brada, D., & Schekman, R.

Times Cited: 211

A primer on vesicle budding

Cell, 97, 2, Apr 16 1999, Pages 145-148

Springer, S., Spang, A., & Schekman, R.

Times Cited: 209

Protein localization and membrane traffic in yeast

Annual Review of Cell Biology, 1, 1985, Pages 115-143

Schekman, R.

Times Cited: 207

Gene dosage-dependent secretion of yeast vacuolar carboxypeptidase-y

Journal of Cell Biology, 102, 5, May 1986, Pages 1551-1557

Stevens, T. H., Rothman, J. H., Payne, G. S., & Schekman, R.

Times Cited: 199

Topology and functional domains of sec63p, an endoplasmic-reticulum membrane-protein required for secretory protein translocation

Molecular and Cellular Biology, 12, 7, Jul 1992, Pages 3288-3296

Feldheim, D., Rothblatt, J., & Schekman, R.

Times Cited: 195

Localization of components involved in protein-transport and processing through the yeast golgi-apparatus

Journal of Cell Biology, 112, 1, Jan 1991, Pages 27-37

Franzusoff, A., Redding, K., Crosby, J., Fuller, R. S., & Schekman, R.

Times Cited: 193

Multienzyme systems of DNA-replication

Science, 186, 4168, 1974, Pages 987-993

Schekman, R., Weiner, A., & Kornberg, A.

Times Cited: 180

Protein translocation across biological membranes

Science, 310, 5753, Dec 2 2005, Pages 1452-1456

Wickner, W., & Schekman, R.

Times Cited: 179

The sec13p complex and reconstitution of vesicle budding from the er with purified cytosolic proteins

Embo Journal, 12, 11, Nov 1993, Pages 4073-4082

Salama, N. R., Yeung, T., & Schekman, R. W.

Times Cited: 167

An mf alpha-1-suc2 (alpha-factor-invertase) gene fusion for study of protein localization and gene-expression in yeast

Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences, 80, 23, 1983, Pages 7080-7084

Emr, S. D., Schekman, R., Flessel, M. C., & Thorner, J.

Times Cited: 162

Gtp-binding ypt1 protein and ca-2+ function independently in a cell-free protein-transport reaction

Proceedings of the National Academy of Sciences of the United States of America, 87, 1, Jan 1990, Pages 355-359

Baker, D., Wuestehube, L., Schekman, R., Botstein, D., & Segev, N.

Times Cited: 162

Sec21 is a gene required for er to golgi protein-transport that encodes a subunit of a yeast coatomer

Nature, 360, 6404, Dec 10 1992, Pages 603-605

Hosobuchi, M., Kreis, T., & Schekman, R.

Times Cited: 162

Nucleation of copii vesicular coat complex by endoplasmic reticulum to golgi vesicle snares

Science, 281, 5377, Jul 31 1998, Pages 698-700

Springer, S., & Schekman, R.

Times Cited: 158

Dynamics of the copii coat with gtp and stable analogues

Nature Cell Biology, 3, 6, Jun 2001, Pages 531-537

Antonny, B., Madden, D., Hamamoto, S., Orci, L., & Schekman, R.

Times Cited: 154

Differential trafficking and timed localization of two chitin synthase proteins, chs2p and chs3p

Journal of Cell Biology, 135, 3, Nov 1996, Pages 597-610

Chuang, J. S., & Schekman, R. W.

Times Cited: 153

Localized secretion of acid-phosphatase reflects the pattern of cell-surface growth in saccharomyces-cerevisiae

Journal of Cell Biology, 86, 1, 1980, Pages 123-128

Field, C., & Schekman, R.

Times Cited: 152

Bip and sec63p are required for both co- and posttranslational protein translocation into the yeast endoplasmic-reticulum

Proceedings of the National Academy of Sciences of the United States of America, 92, 21, Oct 10 1995, Pages 9643-9646

Brodsky, J. L., Goeckeler, J., & Schekman, R.

Times Cited: 151

A test of clathrin function in protein secretion and cell-growth

Science, 230, 4729, 1985, Pages 1009-1014

Payne, G. S., & Schekman, R.

Times Cited: 147

Invertase signal and mature sequence substitutions that delay intercompartmental transport of active enzyme

Journal of Cell Biology, 100, 5, 1985, Pages 1664-1675

Schauer, I., Emr, S., Gross, C., & Schekman, R.

Times Cited: 143

A New form of DNA-polymerase iii and a copolymerase replicate a long, single-stranded primer-template

Proceedings of the National Academy of Sciences of the United States of America, 70, 6, 1973, Pages 1764-1767

Wickner, W., c, R., Geider, K., & Kornberg, A.

Times Cited: 142             

Membrane fusion

Nature Structural & Molecular Biology, 15, 7, Jul 2008, Pages 658-664

Wickner, W., & Schekman, R.

Times Cited: 142

Reconstitution of protein translocation from solubilized yeast membranes reveals topologically distinct roles for bip and cytosolic hsc70

Journal of Cell Biology, 120, 1, Jan 1993, Pages 95-102

Brodsky, J. L., Hamamoto, S., Feldheim, D., & Schekman, R.

Times Cited: 136

Coatomer, arf1p, and nucleotide are required to bud coat protein complex i-coated vesicles from large synthetic liposomes

Proceedings of the National Academy of Sciences of the United States of America, 95, 19, Sep 15 1998, Pages 11199-11204

Spang, A., Matsuoka, K., Hamamoto, S., Schekman, R., & Orci, L.

Times Cited: 135

Er export: Public transportation by the copii coach

Current Opinion in Cell Biology, 13, 4, Aug 2001, Pages 438-443

Antonny, B., & Schekman, R.

Times Cited: 133

10 proteins required for conversion of phi-x174 single-stranded-DNA to duplex form invitro - resolution and reconstitution

Journal of Biological Chemistry, 250, 15, 1975, Pages 5859-5865

Schekman, R., Weiner, J. H., Weiner, A., & Kornberg, A.

Times Cited: 128

The yeast sec17 gene-product is functionally equivalent to mammalian alpha-snap protein

Journal of Biological Chemistry, 267, 17, Jun 15 1992, Pages 12106-12115

Griff, I. C., Schekman, R., Rothman, J. E., & Kaiser, C. A.

Times Cited: 125

Regulated import and degradation of a cytosolic protein in the yeast vacuole

Nature, 350, 6316, Mar 28 1991, Pages 313-318

Chiang, H. L., & Schekman, R.

Times Cited: 122

Clathrin - a role in the intracellular retention of a golgi membrane-protein

Science, 245, 4924, Sep 22 1989, Pages 1358-1365

Payne, G. S., & Schekman, R.

Times Cited: 121

Sec62 encodes a putative membrane-protein required for protein translocation into the yeast endoplasmic-reticulum

Journal of Cell Biology, 109, 6, Dec 1989, Pages 2653-2664

Deshaies, R. J., & Schekman, R.

Times Cited: 121

Sec11 is required for signal peptide processing and yeast-cell growth

Journal of Cell Biology, 106, 4, Apr 1988, Pages 1035-1042

Bohni, P. C., Deshaies, R. J., & Schekman, R. W.

Times Cited: 120

Purification and characterization of sar1p, a small gtp-binding protein required for transport vesicle formation from the endoplasmic-reticulum

Journal of Biological Chemistry, 268, 2, Jan 15 1993, Pages 873-879

Barlowe, C., Denfert, C., & Schekman, R.

Times Cited: 118

The yeast clathrin adaptor protein complex 1 is required for the efficient retention of a subset of late golgi membrane proteins

Developmental Cell, 2, 3, Mar 2002, Pages 283-294

Valdivia, R. H., Baggott, D., Chuang, J. S., & Schekman, R. W.

Times Cited: 117

Cargo selection into copii vesicles is driven by the sec24p subunit

Embo Journal, 21, 22, Nov 15 2002, Pages 6105-6113

Miller, E., Antonny, B., Hamamoto, S., & Schekman, R.

Times Cited: 115

Protein-transport to the vacuole and receptor-mediated endocytosis by clathrin heavy chain-deficient yeast

Journal of Cell Biology, 106, 5, May 1988, Pages 1453-1461

Payne, G. S., Baker, D., Vantuinen, E., & Schekman, R.

Times Cited: 115

The yeast sec53 gene encodes phosphomannomutase

Journal of Biological Chemistry, 263, 19, Jul 5 1988, Pages 9155-9161

Kepes, F., & Schekman, R.

Times Cited: 115

Cytosolic sec13p complex is required for vesicle formation from the endoplasmic-reticulum invitro

Journal of Cell Biology, 120, 4, Feb 1993, Pages 865-875

Pryer, N. K., Salama, N. R., Schekman, R., & Kaiser, C. A.

Times Cited: 112

The role of stress proteins in membrane biogenesis

Trends in Biochemical Sciences, 13, 10, Oct 1988, Pages 384-388

Deshaies, R. J., Koch, B. D., & Schekman, R.

Times Cited: 111

Yeast secretory mutants that block the formation of active cell-surface enzymes

Journal of Cell Biology, 98, 1, 1984, Pages 35-43

Ferronovick, S., Novick, P., Field, C., & Schekman, R.

Times Cited: 110

Sec7 encodes an unusual, high molecular-weight protein required for membrane traffic from the yeast golgi-apparatus

Journal of Biological Chemistry, 263, 24, Aug 25 1988, Pages 11711-11717

Achstetter, T., Franzusoff, A., Field, C., & Schekman, R.

Times Cited: 105

A subset of yeast vacuolar protein sorting mutants is blocked in one branch of the exocytic pathway

Journal of Cell Biology, 156, 2, Jan 21 2002, Pages 271-285

Harsay, E., & Schekman, R.

Times Cited: 104

Copii and secretory cargo capture into transport vesicles

Current Opinion in Cell Biology, 9, 4, Aug 1997, Pages 477-483

Kuehn, M. J., & Schekman, R.

Times Cited: 103

Binding of secretory precursor polypeptides to a translocon subcomplex is regulated by bip

Cell, 88, 1, Jan 10 1997, Pages 85-96

Lyman, S. K., & Schekman, R.

Times Cited: 101

Gpi anchor attachment is required for gas1p transport from the endoplasmic reticulum in cop ii vesicles

Embo Journal, 15, 1, Jan 2 1996, Pages 182-191

Doering, T. L., & Schekman, R.

Times Cited: 101

The lumenal domain of sec63p stimulates the atpase activity of bip and mediates bip recruitment to the translocon in saccharomyces cerevisiae

Journal of Cell Biology, 137, 7, Jun 30 1997, Pages 1483-1493

Corsi, A. K., & Schekman, R.

Times Cited: 101

Chs1p and chs3p, two proteins involved in chitin synthesis, populate a compartment of the saccharomyces cerevisiae endocytic pathway

Molecular Biology of the Cell, 7, 12, Dec 1996, Pages 1909-1919

Ziman, M., Chuang, J. S., & Schekman, R. W.

Times Cited: 100

Clustering and endocytosis of membrane receptors can be induced in mature erythrocytes of neonatal but not adult humans

Proceedings of the National Academy of Sciences of the United States of America, 73, 11, 1976, Pages 4075-4079

Schekman, R., & Singer, S. J.

Times Cited: 100

Export of major cell-surface proteins is blocked in yeast secretory mutants

Journal of Cell Biology, 96, 2, 1983, Pages 541-547

Novick, P., & Schekman, R.

Times Cited: 100

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